Tatsuya Yoshida, Mikito Takefuji, and Toyoaki Murohara in the Department of Cardiology, Nagoya University Graduate School of Medicine, identified an enzyme, alpha-kinase 2 (ALPK2) that is specifically ...
ALPK2 is a heart-specific enzyme that regulates cardiac muscle flexibility by activating the TPM1 gene Lower ALPK2 levels are linked to heart stiffness, while increased ALPK2 can protect against heart ...
Heart failure with preserved ejection function is a lethal form of heart failure, with few effective treatments. A team has now identified an enzyme, alpha-kinase 2 (ALPK2), that is specifically ...
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