Aging is a biological process that no one can avoid. Ideally, growing old should be a time to relax and enjoy the fruits of your labor. Aging also has a darker side, however, often linked to disease.

As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, ...

Aging is the primary risk factor for numerous life-threatening diseases and has long been a central focus of biological research. Epigenetic reprogramming, a process that can modulate cell fate and ...

A small tweak to mitochondrial energy production led to big gains in health and longevity. Mice engineered to boost a protein that helps mitochondria work more efficiently lived longer and showed ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...

That inevitability of growing older might not be as fixed as we once believed. Emerging research has begun challenging our most fundamental assumptions about aging, revealing that cellular ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Life relies on the storage and transmission of information. In complex organisms, this information exists in two primary forms: the genome and the epigenome. While genetic information remains largely ...

Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and aging are locked in a vicious circle: senescence of liver cells accelerates fat accumulation, inflammation and ...