We have developed a luminogenic CYP2B6 assay for biochemical CYP2B6 inhibition and for cell-based CYP2B6 induction studies. Here we present the CYP2B6 luminogenic assay characterization and ...
CPA is a widely used alkylating drug in cancer chemotherapy and immunosuppression. A high degree of interpatient variation in the pharmacokinetic parameters of CPA and its active 4-hydroxylated ...
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