Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to ...

Understanding the genetic mechanisms linking genome variations, such as single-nucleotide polymorphisms (SNPs), to phenotypes ...

Researchers used single-nucleus multiomics to map gene expression and regulation across three brain regions in sporadic early ...

There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...

Researchers have developed a new computational approach that uncovers possible drugs for specific cellular targets for ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...