Cancer metastasis is the process by which cancerous cells spread from the primary tumor site to other regions of the body. Despite advancements in cancer research, the factors driving the selective ...
Scientists in Japan may have come across a new ALS gene, according to the February 6 Cell Reports. Koichi Matsuda, University of Tokyo, and colleagues found that the enzyme peptidylarginine deiminase ...
Image Caption: The reaction mechanism of protein arginine citrullination is catalyzed by PAD. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative ...
Peptidyl-arginine deiminase 2 (PAD2) enzyme converts arginine amino acid residues in histone proteins into citrulline groups and promotes tumor cell proliferation in pancreatic ductal adenocarcinoma, ...
Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease. This process, driven by the enzyme ...
My research focuses on determining the role of peptidylarginine deiminase (PAD) enzymes in female reproduction and associated diseases. The PAD enzymes post-translationally convert positively charged ...