Dendritic cells occupy a pivotal role at the nexus of metabolism and immune regulation, employing distinct bioenergetic programmes to calibrate antigen uptake, processing and presentation. In their ...

A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial ...

The mitochondria are a membrane-bound cellular organelle commonly referred to as the “powerhouse” of the cell. Their main ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their ...

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or "tolerate" molecules found on ...

Immunotherapy uses a person's own immune system to fight cancer. Immune checkpoint inhibitors are one class of immunotherapy that block specific proteins from slowing the immune response. As a result, ...

(MEMPHIS, Tenn. – April 02, 2026) St. Jude Children’s Research Hospital scientists have discovered how tumors disable immune “gatekeeper” cells that alert the rest of the immune system to the presence ...