From structure confirmation to methodology improvements, making complex natural products has driven innovation in organic ...

"This study provides a striking example contradicting the trope of structural simplicity at high densities. We hope that this synthesis of the aromatic hexazine anion, together with that of the ...

Chemists have developed a method to furnish a range of molecules with a trifluoromethyl group attached to a sulfur, nitrogen or oxygen atom. Their procedure avoids the use of PFAS reagents. It thus ...

One of the important objectives of green chemistry is the use of eco-friendly solvents and catalysts to perform chemical reactions. Catalysts such as organocatalysts, enzymes, and ionic liquids have ...

Macrolactones—large ring lactones—are core components of many natural products and pharmaceutical agents. Traditional synthetic routes rely on seco acids activated with condensing reagents, often ...

The most common theory about the emergence of prebiotic amino acids can’t account for cysteine, so origin-of-life researchers have proposed that it is a product of evolution. A new study proposes a ...

With artificial intelligence, scientists can design increasingly complex small molecule structures. Automation is critical for transforming these compounds from designs on a screen into actual ...

AstraZeneca will partner with DeepMatter to improve the productivity and reproducibility of compound synthesis by combining the pharma giant’s automated compound synthesis platform with DeepMatter’s ...