DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

It is still not fully understood how, despite having the same set of genes, cells turn into neurons, bones, skin, heart, or roughly 200 other kinds of cells, and then exhibit stable cellular behavior ...

NIH funding has allowed scientists to see the DNA blueprints of human life—completely. In 2022, the Telomere-to-Telomere Consortium, a group of NIH-funded scientists from research institutions around ...

Electronic genome mapping (EGM) detects and validates structural variants in cancer genomes with improved accuracy over existing platforms, including optical mapping technologies PROVIDENCE, R.I., Oct ...

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose intimate folds govern the destiny of cells. A mapping of unprecedented precision ...

In a new study published in Nature Communications titled, “The reference genome of the human diploid cell line RPE-1,” researchers from University of Rome La Sapienza have produced the first reference ...

Today, genomics is saving countless lives and even entire species, thanks in large part to a commitment to collaborative and open science that the Human Genome Project helped promote. Twenty-five ...

Twenty-five years ago today, on July 7, 2000, the world got its very first look at a human genome — the 3 billion letter code that controls how our bodies function. Posted online by a small team at ...