New research shows that cancer cells don’t just grow; they adapt when stressed. When squeezed inside tissues, they transform into more invasive, drug-resistant versions of themselves. A protein called ...

Researchers at NYU Langone Health propose a model that could explain how cancer cells adapt to environmental stress, an approach that may lead to new therapies. Published online April 15 as the cover ...

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched. The technology has largely been tested in cells ...

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, ...

Cancer treatment has come a long way, but many of today’s therapies still come with steep costs: not just financial, but physical and emotional too. Chemotherapy and radiotherapy remain vital tools, ...

Scientists have recently been learning more about the importance of small bits of circular genetic material known as extrachromosomal DNA (ecDNA). These little circles of DNA can hitch a ride with ...

“There has never really been an integrated explanation as to why cancer cells develop plasticity,” said Antonio Iavarone, M.D. “That’s what our study does. We’ve now revealed how the plasticity of ...

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune ...

After nearly 100 years of development, treatments that bolster the body's immune system to fight cancer are coming of age – ...

Structural insight into KRAS conformational cycling exposed temporary binding opportunities, overturning the “undruggable” ...

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune ...

When activated by its target, the newly characterized molecule rips the genome apart, a lethal move that researchers can ...