This illustration shows the major cell types affected by cellular senescence in various skeletal diseases. As the body ages, senescent cells accumulate in different tissues—including bone, cartilage, ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers at the University of Basel have now discovered that these skeletal cells do not just ...