The cells in human bodies are subject to both chemical and mechanical forces. But until recently, scientists have not understood much about how to manipulate the mechanical side of that equation. That ...

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen, talks to News-Medical Life Sciences about the ongoing ...

New winning strategy uncovered in mechanical cell competition The molecular factors and biochemical signals involved in cell ...

Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is ...

Structures called desmosomes connect cells to each other and transfer mechanical stress. They are especially important in tissues under continual mechanical stress, such as heart muscle (pictured).

Millions of people worldwide are diagnosed with cancer every year. In advanced tumor diseases, cancer cells detach from the ...

As a part of our immune defenses, cytotoxic T cells – or killer T cells – seek out and destroy cells that are infected or cancerous. This process is essential for the body's defense against diseases.

Trial of strength at the cellular level: Cells are in constant competition with each other and so eliminate diseased or unwanted cells. Cell competition is therefore a central principle for ...

Intercellular forces generate distinct patterns of extrusion: high compressive forces (top panel) drive apoptotic cell extrusion toward the upper side, while lower compressive forces (bottom panel) ...