Children's Hospital of Philadelphia Study May Help Explain Why Some Children with Sepsis or Organ Failure Face a Harder Recovery

A Children's Hospital of Philadelphia (CHOP) research team, working with collaborators across Penn and several national institutions, reported that many critically ill children who develop multiple ...
Frontiers

Endothelial Dysfunction, Vascular-Organ Crosstalk, and Therapeutic Targets in Cardiovascular Disease

Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide. A growing body of evidence identifies endothelial dysfunction as ...
Medical Xpress

The international system for assessing organ dysfunction in critically ill patients is updated after thirty years

The updated version of the Sequential Organ Failure Assessment (SOFA), the global reference system in intensive care medicine used to assess the degree of organ dysfunction in critically ill patients, ...
News Medical

Modeling the interaction between the intestine and liver in a multi-organ microphysiological system for studying metabolic-dysfunction associated steatotic liver disease

The connection between the human liver and the intestine is unique, and the “gut-liver axis” plays a vital role in regulating liver disease pathology. When homeostasis is disturbed, changes in dietary ...