A high-frequency brain signal in the frontal cortex is linked to OCD compulsions. Targeted deep brain stimulation rapidly reduced symptoms in severe cases.

A specific pattern of brain activity in a frontal brain region is linked to compulsive behaviors like excessive hand washing, ...

(Santa Barbara, Calif.) — Life can be tricky. We have so many decisions to make. It’s a good thing we have an orbitofrontal cortex and hippocampus to help us. These areas of the brain, according to ...

As humans and other animals navigate their surroundings and experience different things, their brain creates so-called cognitive maps, which are internal representations of environments or tasks.

Now, scientists from the University of Warwick have made important progress in learning what causes alcohol addiction in the ...

A new study links anxiety, a brain structure called the orbitofrontal cortex, and optimism, finding that healthy adults who have larger OFCs tend to be more optimistic and less anxious. The new ...

Neuronal pathways originating from the orbitofrontal cortex (OFC) of the brain participate in different adaptive behaviors, but which pathways are used for distinct adaptive strategies remains unclear ...

Study reveals how aging accelerates molecular changes in the brain, offering new hope for tackling cognitive decline and mental illness. Resource: Single-nucleus transcriptomic profiling of human ...

Overexpression of Shisa7 in the orbitofrontal cortex in drug-free rats induced comparable up and down changes in gene expression as that induced by the self-administration of heroin. The concordant ...