Organoids are miniature tissue or organ models formed by stem cells (including pluripotent stem cells, tissue-specific adult ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

Lung diseases like emphysema or chronic obstructive pulmonary disease are a leading cause of death worldwide. With the advent of COVID-19, these diseases have only become more prevalent. Despite the ...

A frequently reported fact in the drug discovery and development industry is that approximately 90 % of drug candidates reaching clinical trials fail, with even higher amounts discarded before ...

What is an Organ-on-a-Chip? An organ-on-a-chip is a microfluidic device that simulates the key functions and physiological responses of a specific human organ or organ system on a miniaturized scale.

A 'humanized' mouse model equipped with the immune system of a patient who needs an organ transplant beats current measures for identifying the best potential living donor, scientists report. A ...