For a monovalent species, a simple calculation that does not assume partitioning of the ionized species in the oil phase can provide an accurate estimate of the distribution coefficient. Get the ...

This is a preview. Log in through your library . Abstract The history of the relationship of biological activity to partition coefficient and related properties is briefly reviewed. The dominance of ...

Partition coefficients and solubility are fundamental parameters in the study of organic compounds, characterising the distribution of molecules between immiscible solvents. These properties are ...