Recombinant adeno-associated virus (rAAV) is currently used as vector in about 250 clinical trials for gene therapy (Bulcha et al., 2021). Nonetheless, there are still several challenges concerning ...

Current potential bioprocess solutions for the scaleup of adherent cells include cell stacks, robotic flask handling, packed-bed culture, hollow-fiber bioreactors, and microcarriers or aggregate ...

However, LV manufacturing methods require upgrading to meet the current demands. Early phase clinical trials require extensive amounts of LVs, 8 which are still mostly produced by non-standardized, ...

Bose Corporation has introduced the 3DCulturePro™ system, a new multi-specimen perfusion bioreactor designed for biologists, biomedical researchers and scientists who require reproducible and reliable ...