Intracellular protein editing. Credit: Science (2025). DOI: 10.1126/science.adr5499. https://www.science.org/doi/10.1126/science.adr5499 University of Pennsylvania ...
Amino acids are like Lego blocks—they can be linked together to form complex structures called proteins. Unlike Legos, ...
Measure His-tag protein expression directly from crude lysates with consistent, reproducible protein quantification across ...
Understanding how proteins behave in living systems is central to biology. Yet, for decades, researchers have relied on overexpression models or antibody-based detection methods that can distort the ...
Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future therapies. There is no known cure for Huntington's disease. A genetic ...
Bioluminescent assays are essential tools for tracking protein activity, cell signaling pathways and cellular dynamics. These assays provide high sensitivity, low background noise, and flexibility for ...
These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com. S. Cabantous et al ...