With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology ...
The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology. As critical regulators of gene expression, RBPs ...
New findings from Karolinska Institutet reveal how the gene HNRNPU coordinates several fundamental molecular processes during ...
The interaction between circular RNA (circRNA) and RNA-binding protein (RBP). Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that ...
Scientists found that messenger RNA (mRNA) molecules that carry genetic instructions to the far reaches of neurons in the brain tend to cluster together mostly because they are abundant, not because ...
In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, ...
Different DNA Structures Nucleate the Folding of Proteins to form specific complexes that modulate the readout of ...
In 2021, research led by Ryan Flynn, MD, PhD, and his mentor, Nobel laureate Carolyn Bertozzi, PhD, opened a new chapter in biology, characterizing a new kind of player on the cell surface: glycoRNAs.
A novel tRNA fragment limits UV-driven photoageing by protecting collagen and mRNA stability. Discover the mechanism and its therapeutic potential. Read more.