A new study shows how one of the cell's most important energy-producing machines is built. Researchers at Karolinska ...

A new study in Nature Communications shows how one of the cell's most important energy-producing machines is built.

(Top left) Research aim. (Top right) Schema of mitochondrial respiratory chain supercomplex localization and function. (Bottom left) Analysis of supercomplex formation by hrCN-PAGE and in-gel activity ...

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

Leigh syndrome is a fatal pediatric neurodegenerative disorder caused by mitochondrial dysfunction, most often due to defects ...

Researchers mapped late steps in the formation of the human respirasome, a large protein assembly that drives mitochondrial ...