Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal. As a result, the disc's ability to withstand ...

It feels like back pain comes for many of us at some point in our lives, and it’s tricky to treat. A new gene therapy, which repairs damaged discs and reduces pain, has shown promise in mouse tests.

Back or spinal decompression refers to a group of treatments used to relieve pressure on spinal discs. A healthcare professional may recommend surgical and nonsurgical therapies for decompression.

A bulging disc in your lower back is most often caused by naturally occurring changes as you age. Most bulging discs don’t cause symptoms, but they may progress to become herniated discs. Lower back ...

Neural foraminal stenosis occurs when the space a spinal nerve travels through narrows, causing nerve irritation and ...

Schematic diagram depicting the mechanism of the rigid matrix regulating cell glycolysis in degenerated NPCs. In degenerated NP tissue, MRTF-A was activated by increased matrix stiffness and ...

Bones called vertebrae make up your spine. Muscles and ligaments connect your vertebrae to each other. Between the vertebrae lie soft, flat discs that provide cushioning and support. Each vertebra ...

Low back pain is the most prevalent musculoskeletal condition worldwide and is closely tied to the progressive degeneration of intervertebral discs. Aging remains the strongest risk factor for this ...

Low back pain is one of the most common reasons patients see primary care doctors. To understand this condition, it’s necessary to understand the anatomy of the low back. The lower (lumbar) spine ...