Combining MAGE with CAGE allowed the genome to manipulated as an editable and evolvable template. Scientists have combined a recently developed technique known as multiplex automated genome ...
We have gone further than ever before in creating life that is unlike anything that has evolved naturally. The genome of an Escherichia coli bacterium has been redesigned on a computer to use just 57 ...
The DNA of nearly all life on Earth contains many redundancies, and scientists have long wondered whether these redundancies served a purpose or if they were just leftovers from evolutionary processes ...
An illustration of E. coli. Scientists have been racing to shrink the genetic code of this bacterium. Kateryna Kon / Science Photo Library via Getty Images The DNA of nearly all life on Earth is made ...
Most organisms on Earth have the same basic genetic code, but it comes with some flaws. Scientists sought to work out those errors by creating their own artificial genome, which replaced E. coli’s ...
When Patrick Yizhi Cai reflects on the state of synthetic genomics, he recalls the Big DNA Contest. Launched in 2004, the competition challenged synthetic biologists to design a novel, functional ...
As scientists gain an increasing ability to build synthetic genomes to specific design criteria, this is enabling the production of cells that have beneficial properties not found in the natural world ...
Liquid culture flasks of bacteria grown in yellow broth covered with tinfoil on a shaker. Bacterial strains needed to be tested every step of the way to create the highly compressed genome. Credit: ...
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