Support for the hypothesis that transcription is initiated before the operator region of the trp-operon of E. coli, and that the repressor, in binding to the operator region, directly blocks the ...

Elevated tryptophan metabolism correlates with improved csDMARD response, reduced inflammation, and better clinical outcomes in rheumatoid arthritis patients. Multiomics analysis identified ...

Background Both host and microbe metabolism of tryptophan (Trp) is altered in diabetes; however, the molecular mechanisms are ...

Peptides are gradually emerging as middle-sized therapeutic agents in addressing unmet medical needs. Compared to small-molecule drugs, peptides can target complex biological processes more precisely ...