Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

For her Ph.D. at VUB and KULeuven, Aarushi Caro created a kind of systematics for dendritic cells, a special group of immune cells in the fight against cancer. Until now, there was a lot of confusion ...

MIT engineers have developed a new way to amplify the T-cell response to mRNA vaccines—an advance that could lead to much more powerful cancer vaccines and stronger protection against infectious ...

In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...

Electron microscope image of neurons in the cerebellum. This slice through the cells in the cerebellum shows a dendritic branch of a Purkinje cell and its side arms (yellow) receiving several ...

A new study has revealed that a special group of cells in the intestines tamp down the immune responses caused by exposure to food proteins. Called 'tolerogenic dendritic cells,' these cells enable ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring ...

In the article that accompanies this editorial, van ‘t Land et al 24 report that additional pancreatic cancer adjuvant therapy with autologous, monocyte-derived dendritic cells (DCs) loaded with ...