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Taking images of tiny structures within cells is tricky business. One technique, cryogenic electron tomography (cryoET), ...

Researchers have combined two microscopic imaging techniques in one microscope, providing scientists with a high-resolution method of tracking single molecules in a cellular context. The development ...

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Chemists discover how key contrast agent works, paving a way to create new markers needed for correlative microscopy that can image the structure and signaling of cells at the same time. Two labs at ...

With the inventions of transmission electron microscopy (TEM) in 1931 and scanning electron microscopy (SEM) shortly after in 1937, scientists gained an unprecedented ultrastructural view of the ...

(a) A scanning electron microscope (SEM) image of the nanoneedle probe used for the measurements. (b) Elasticity map of a 1 µm × 1 µm area on the nuclear surface, showing the change in elasticity ...