In the methylcyclohexanone example above, the trisubstituted enolate deprotonates more quickly: it is the kinetic enolate. The tetrasubstituted enolate is more stable, and dominant in thermodynamic …

Aug 16, 2022 · Enolates can be formed through removing the proton on carbons adjacent to a carbonyl (i.e. the “ alpha-carbon “). The resulting anions are much more stable than typical alkanes since the …

Since the negative charge of an enolate anion is delocalized over the alpha-carbon and the oxygen, as shown earlier, electrophiles may bond to either atom. Reactants having two or more reactive sites …

Enolates, or oxyallyl anions, are versatile reagents for the formation of α-substituted carbonyl compounds and are therefore important intermediates for the synthesis of complex molecules.

Enolates are resonance-stabilized anions that play a crucial role in organic chemistry as versatile nucleophiles. Understanding their formation, reactions, and applications is essential for mastering the …

Apr 16, 2025 · Enolates are reactive intermediates in organic chemistry that play a central role in forming carbon–carbon bonds. They are formed by deprotonating the α-hydrogen of carbonyl compounds …

Apr 22, 2024 · One of the main characteristics of the carbonyl group is that the hydrogens adjacent to the carbonyl carbon are acidic and can react with certain bases. If this occurs, the aldehyde or …