The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new …

The replisome is a molecular machine responsible for DNA replication in all living organisms. It unwinds double-stranded DNA and synthesizes new complementary strands, creating two identical copies of …

Replisomes are machines composed of numerous proteins that function together to accomplish the replication of duplex DNA, forming two new DNA duplexes required for cell division.

Jan 24, 2019 · The DNA replisome is a multiprotein machine that performs concerted parental strand separation and RNA-primed DNA synthesis on both strands. A helicase is central to all replisomes by …

Dec 13, 2025 · The replisome is a large protein complex that carries out DNA replication, starting at the replication origin. It contains several enzymatic activities, such as helicase, primase and DNA...

Aided by the replisome structure, here we integrate existing genetic, biochemical and structural data to review the replisome organization and ways that it can be broken and reassembled to complete …

Oct 25, 2021 · The human replisome is an elaborate arrangement of molecular machines responsible for accurate chromosome replication.